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Signs or symptoms of serotonin syndrome'

Irritability, Delirium, Change, Fits, Restlessness, Increased middle rate, Perspiration, Shivering, Tremor, Mental status changes, Restlessness, Increased reflexes, Increased reflexes, Stiffness, Shaking, Pain in the stomach, Diarrhoea, Perspiration, Increased temperature, High blood pressure. All these are symptoms of serotonin syndrome. All may come usually in the first 24 hours following taking a great overdose of serotonin drugs. This signs or symptoms take cerebral processes stage, visceral nervous system degree and SoNS stage. Serotonin Syndrome look often soon after overdose of serotonin drugs and drug combination that increase synaptic serotonin. Drugs which are know to stimulate high levels of serotonin are: MAOIs, TCAs, SSRIs, SNRIs, Bupropion, Tramadol, Fentany, Oxycodone, Hydrocodone, MDMA, MDA, Amphetamine, Sibutramine, Cocaine, Triptans, LSD, Panax Ginseg, Nutmed, Yohimbe, Syrian Rue, Ritonavir, Granisetron, Olanzapine, Valproate, Buspirone, Lithium, Linezolid, Dextromethorphan, Risperidone, Trypthophan, L-Dopa, Valproate, Pep pill. Due to the fact serotonin syndrome it's definitely not tested in the laboratory for diagnosis, symptoms are the one which need noticed. The greatest set of criteria to utilize to diagnose serotonin toxicity is Hunter Serotonin Toxicity Criteria.

Treatment for serotonin syndrome are because follows: discontinuing drugs which made the overdose posible as well as drugs which can lead administration of serotonin antagonist (eg. cyproheptadine) for cut cases of toxicity for agitation, muscle mass hardness and capture like movements, benzodiazepines (Valium, Ativan) Intra venous liquids Because serotonin syndrome is not all to easy to diagnose, protection is wanted for any 5-hydroxytryptamine drugs mixture of that might cause 5-hydroxytryptamine toxicity.


Dunkley, EJ, Isbister, GK, Sibbritt, D, Dawson, AH, Whyte, IM, The Hunter Serotonin Toxicity Criteria: simple and accurate diagnostic decision rules for serotonin toxicity, QJM 2003; 96:635-642 Prator BC. Serotonin Syndrome. J Neurosci Nurs. 2006 Apr;38(2):102-5. Ford MD, Clinical Toxicology. 1st ed. Philadelphia, Pa: WB Saunders; 2001:150, 522, 547, 550.